Skip to main content
Fig. 1 | Pediatric Rheumatology

Fig. 1

From: Exploring the intersection of adverse childhood experiences, pediatric chronic pain, and rheumatic disease

Fig. 1

Chronic pain syndromes and rheumatologic disease share overlapping driving factors. The etiologies of chronic pain and rheumatologic disease are complex and manifold. However, genetic predisposition, environmental factors, and chronic stress are all relevant. This figure proposes a model for how ACEs may play an underappreciated (but addressable) role in pathogenesis for both disease processes through neuroendocrine changes

Back to article page

Pediatric Rheumatology

ISSN: 1546-0096