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Table 1 Clinical and demographic features of our cohort of children with JIA

From: In a large Juvenile Idiopathic Arthritis (JIA) cohort, concomitant celiac disease is associated with family history of autoimmunity and a more severe JIA course: a retrospective study

Total patients with JIA

329

Sex, N (%)

F

246 (74.8)

M

83 (25.2)

Median Age, years (IQR)

At JIA onset

4 (2.2–7.8)

Present

12.5 (9.1–16.1)

Follow-up duration, years (IQR)

 

5.1 (2.7–8.9)

JIA subtypes, N (%)

Oligoarticular

215 (65.3)

RF negative polyarticular

54 (16.4)

RF positive polyarticular

3 (0.9)

Systemic

29 (8.8)

Psoriatic

8 (2.4)

ERA

5 (1.5)

Undifferentiated

15 (4.6)

Family history of

Autoimmunity, N (%)

Yes

154 (46.8)

No

175 (53.2)

Co-occurrence of

autoimmune disorders, N (%)

Uveitis

48 (14.6)

Presence of thyroid antibodies

23 (7)

Autoimmune thyroiditis

20 (6.1)

Celiac disease

8 (2.4)

IBD

4 (1.2)

Type 1 diabetes

1 (0.3)

Therapy, N (%)a

NSAID and/or intra-articular CS only

81 (24.6)

MTX and/or other cDMARDs

240 (72.9)

bDMARDs

134 (40.7)

  1. JIA Juvenile Idiopathic Arthritis, N Number, IQR Interquartile Range, ERA Enthesitis-Related Arthritis, IBD Inflammatory Bowel Diseases, IBD Inflammatory Bowel Disease, NSAID Nonsteroidal Anti-inflammatory Drug, CS Corticosteroid, MTX Methotrexate, cDMARDs conventional Disease-Modifying Anti-Rheumatic Drugs, bDMARDs biological Disease-Modifying Anti-Rheumatic Drugs, RF rheumatoid factor
  2. aPatients were classified according to JIA treatment administered during the overall disease course