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Table 3 Reasons for switching among all switchers

From: Biologic switching patterns among children with non-systemic juvenile idiopathic arthritis

Reason for switching

1st switch

n (%)

2nd switch

n (%)

 ≥ 3 switches

n (%)

Inefficacy

42 (57)

26 (74)

16 (76)

Injection/infusion reactions

11 (15)

3 (9)

3 (14)

Severe adverse reactions

2 (3)

1 (3)

2 (10)

Psychological effects

2 (3)

  

Non-compliance

1 (1)

1 (3)

 

Uveitis

10 (13)

3 (9)

 

IBD

1 (1)

  

Other reasons

5 (7)

1 (3)

 

In total

74 (37)

35 (17.5)

21 (10.5)