From: Biologic switching patterns among children with non-systemic juvenile idiopathic arthritis
Reason for switching | 1st switch n (%) | 2nd switch n (%) | ≥ 3 switches n (%) |
---|---|---|---|
Inefficacy | 42 (57) | 26 (74) | 16 (76) |
Injection/infusion reactions | 11 (15) | 3 (9) | 3 (14) |
Severe adverse reactions | 2 (3) | 1 (3) | 2 (10) |
Psychological effects | 2 (3) | ||
Non-compliance | 1 (1) | 1 (3) | |
Uveitis | 10 (13) | 3 (9) | |
IBD | 1 (1) | ||
Other reasons | 5 (7) | 1 (3) | |
In total | 74 (37) | 35 (17.5) | 21 (10.5) |