Fig. 4
From: Potential regulatory role of the Nrf2/HMGB1/TLR4/NF-κB signaling pathway in lupus nephritis

IL-1β, TNF- α, and NF- κB protein levels in each group, detected by ELISA. a-c The levels of NF- κB, IL-1β, and TNF- α are significantly upregulated in the model group. Nrf2 overexpression promoted a decrease in all these proteins. (*Compared to the control group, P < 0.05; #Compared with the model group, P < 0.05, n = 6 per group)