Table 1 The main clinical and laboratorial characteristics of each disease that were described compared to those of JIA
From: Chronic limping in childhood, what else other than juvenile idiopathic arthritis: a case series
JIA | COPA syndrome | Neuroblastoma | CNO | Synovial chondromatosis | CACP syndrome | LA | PVS | |
|---|---|---|---|---|---|---|---|---|
Age Of Onset | Oligoarticular 1–3 Yrs FR- Polyarticular Biphasic Trend Between 2–4 Years And 6–12 Years FR + Polyarticular 13–16 Years Systemic 2–6 Years ERA > 6 Years Psoriatic Biphasic Trend Between 6- 8 Years And 12–15 Years | Before 5 yrs of age | Before 6 yrs of age | Before 10 yrs of age | Between 13–15 yrs of age | 2 yrs of age | 12–17 yrs of age | Average 9 yrs of age |
Prevalence | 3.8 to 400/100,000 | < 1 / 1000 000 | 1–5 / 10 000 | 1–9 / 1 000 000 | 1/100 000 | < 1 / 1000 000 | 2.3/100 | 1.8/1,000,000 |
Main Localization | Oligoarticular Large Joints Polyarticular Small Joints Systemic and Psoriatic Large And Small Joints ERA Large Joints of the Lower Extremities | Polyarticular Arthritis Particular Knees And interphalang -eal Joints | Primary Tumor in Adrenal Gland Metastatic Sites: Bones, Bone Marrow, And Liver | Long Bones | Large Joints: Knees, Hips Shoulders | Camptoda ctyly Arthropat hy Of Large Joints Coxa Vara Deformity | Large Joints Arthritis | Knee involvement |
Pain | ++/- | +++ | Dispropor-tionate Pain Level In Contrast To A Mild Swelling | ++ Recurrent pain | + | + | Low Pain Level in Contrast to Major Swelling | - |
Inflammatory Markers | ++/- | +++ | + | + + | - | - | + | + |
Extra- articular Manifestation | Enthesitis (ERA) Dactylitis (ERA and Psoriatic Type) Uveitis (all subtypes) Hepatosplenomeg -aly, Lymphadenopath, Rash, Synovitis (Systemic) | Renal Pulmonary Involvement | Abdominal Painful Palpable Mass Anemia Loss of Weight | Possible combinate with Inflammatory Conditions | None | Pericardia l Involvem ent | Erythema Migrant Nervous system and Cardovas-cular system | None |
Confirmatory Diagnosis | No Specific Tests | Genetic Analysis | Histological examination | No Specific Tests | MR Imaging + Histological Findings | Genetic Analysis | Clinical findings+ Serological Testing | Histological Findings |