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Table 3 Odds of elevated systemic lupus disease activity (SLEDAI ≥ 5) by UVI and season in youth with cSLE from the CARRA Registry

From: Relationship of regional ultraviolet index data with rash and systemic disease activity in youth with childhood-onset systemic lupus: results from the Childhood Arthritis and Rheumatology Research Alliance Registry

 

Crude

Multivariate- Adjusted*

OR

95% CI

P value

OR

95% CI

P value

UVI**

0.99

0.94–1.04

0.64

0.99

0.94–1.04

0.63

UV lag

0.99

0.94–1.03

0.55

0.98

0.94–1.03

0.52

UVI category***

      

Low

1

ref

--

1

ref

--

Moderate

1.02

0.74–1.4

0.91

1.0

0.73–1.38

0.97

High

0.95

0.69–1.3

0.73

0.95

0.69–1.31

0.76

Very high

0.81

0.55–1.21

0.31

0.81

0.54–1.21

0.30

Season^

Winter

1

ref

--

1

ref

--

Spring

1.01

0.73–1.40

0.93

1.02

0.73–1.41

0.92

Summer

1.02

0.74–1.41

0.90

1.05

0.76–1.46

0.76

Fall

1.29

0.92–1.81

0.14

1.29

0.92–1.81

0.14

  1. * adjusted for age, sex, race, and income
  2. **UVI: Ultraviolet Index; UVI, UVI lag, UVI categories, and seasons were all analyzed as separate models
  3. ***UVI categories: low 1–2, moderate 3–5, high 6–7, very high 8–10 [11]
  4. ^seasons defined as: winter January 1-March 31, spring April 1-June 30, summer July 1-September 30, fall October 1-December 31