Table 3 Sampling details and MTX and 7-OH-MTX concentrations
Details of sampling a | Baseline | Follow up |
|---|---|---|
Time to sampling since MTX start (days) | 75 (59–96) | 358 (315–395) |
MTX concentration (nM) | 0.34 (0.28–0.88) | 0.30 (0.24–0.50) |
Dose-normalised MTX (nM/mg) | 0.03 (0.02–0.07) | 0.03 (0.02–0.06) |
7-OH-MTX concentration (nM) | 1.58 (0.76–7.51) | 1.08 (0.59–2.91) |
Dose-normalised 7-OH-MTX (nM/mg) | 0.12 (0.06–0.75) | 0.09 (0.04–0.29) |
MTX:7-OH-MTX ratio | 3.52 (2.93–7.80) | 4.12 (2.48–6.35) |