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Table 3 Laboratory values of patients with sJIA at pre-MAS, onset of MAS and after treatment of-MAS. (n = 34)

From: Single center clinical analysis of macrophage activation syndrome complicating juvenile rheumatic diseases

Laboratory variables

pre-MAS

post-MAS

Post treatment-MAS

n

Median(IQR)

n

Median(IQR)

n

Median(IQR)

WBC (×109/L)

33

14.47(10.25–20.78)

34

7.76(5.54–16.32)

34

12.6(8.83–23.03)

Hb (g/L)

33

104(98.5-112.5)

34

101(92–112)

34

104.5(96-111.8)

PLT (×109/L)

33

258(210–396)*

34

136(99.75–237.8)

34

391.5(215–472)

CRP (mg/L)

32

64.5(25-97.25)

34

25.5(8-62.5)

34

8(8–12)

ESR (mm/h)

29

64(40-85.5)*

28

30(18.25–37.83)

28

16.5(8.25–35.5)

Alb (g/L)

28

35.05(32.8537.83)

34

33.5(31.78–36.18)

34

37.7(35.1-41.55)

ALT (U/L)

32

28.85(13-135.5)*

34

281(61.75–698.3)

34

110.5(43.75–205.3)

AST (U/L)

32

45(26.5-91.25)*

34

191(83.75–541.5)

34

33(24.75–56.25)

LDH (U/L)

29

472(302–611)*

34

825.5(609–1420)

34

382.5(301.8-492.3)

TG (mmol/L)

28

1.40(1.17–2.03)

34

2.04(1.48–2.42)

34

2.36(1.56–3.55)

Dimer (mg/L)

22

1174(584–2517)*

28

2199(664.3–7280)

27

292(180–521)

FIB (g/L)

25

3.58(2.82–4.89)*

31

2.43(1.6–2.71)

30

2.13(1.43–3.87)

SF (µg/L)

29

1500(854.5–2146)*

34

11,014(5546–22,930)

34

1887(740.5–3637)

SF/ESR

28

24.98(15.76–40.95)*

27

411.1(106.6-709.3)

28

89.41(32.75–130.3)

  1. sJIA systemic juvenile idiopathic arthritis, MAS macrophage activation syndrome, WBC white blood cell, Hb Hemoglobin, PLT platelet count, CRP C-reactive protein, ESR erythrocyte sedimentation rate, Alb albumin, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, TG triglycerides, FIB fibrinogen, SF serum ferritin, IQR interquartile range, n number of patients with laboratory data available. * P < 0.05 compared with post-MAS