SLE subjects, N = 47 | TB Ag-NL low, N = 34 | TB Ag-NL high, N = 13 | p-value | |
---|---|---|---|---|
Baseline characteristics | ||||
Age (year) | 12 (10–13) | 12 (11–13) | 11 (9–12) | 0.0603 |
Gender (Male/Female), n (%) | 7/40 (17.50) | 4/30 (13.33) | 3/10 (30) | 0.3769 |
Disease duration since diagnosis (year) | 1 (0.1-3) | 2 (0.6-3) | 0.3 (0.1–0.9) | 0.0273 |
Clinical features of SLE subjects | ||||
SLEDAI ≤ 4 (N = 15) | 2 (2–2) | 2 (2–2) | 0 (0–0) | < 0.0001 |
SLEDAI > 4 (N = 32) | 14 (8-17.50) | 9 (7.50–14) | 20 (15-28.50) | < 0.0001 |
SLICC features, n (%) | ||||
Acute cutaneous lupus | 16/47 (34.04) | 8/34 (23.53) | 8/13 (61.54) | 0.0198 |
Chronic cutaneous lupus | 4/47 (8.51) | 3/34 (8.82) | 1/13 (7.69) | 1.000 |
Neurologic disorder | 2/47 (2.13) | 0/34 (0) | 2/13 (15.38) | 0.0722 |
Oral/nasal ulcers | 4/47 (8.51) | 2/34 (5.88) | 2/13 (15.38) | 0.5723 |
Joint disease | 6/47 (12.77) | 1/34 (2.94) | 5/13 (38.46) | 0.0042 |
Serositis | 5/47 (10.64) | 0/34 (0) | 5/13 (38.46) | 0.0008 |
Hemolytic anemia | 11/47 (23.40) | 4/34 (11.76) | 7/13 (53.85) | 0.005 |
Leukopenia | 7/47 (14.89) | 3/34 (8.82) | 4/13 (30.77) | 0.1723 |
Thrombocytopenia | 3/47 (6.38) | 1/34 (2.94) | 2/13 (15.38) | 0.0503 |
Antiphospholipid syndrome | 2/47 (2.13) | 2/34 (5.88) | 0/13 (0) | 1.000 |
ANA | 45/47 (95.74) | 33/34 (97.06) | 12/13 (92.31) | 0.0774 |
Anti-dsDNA | 45/47 (95.74) | 33/34 (97.06) | 12/13 (92.31) | 0.0003 |
Low complement | 28/47 (59.57) | 17/34 (50) | 11/13 (84.62) | 0.0463 |
Anti-Smith | 7/47 (14.89) | 5/34 (14.71) | 2/13 (15.38) | 1.000 |
Renal involvemen | 21/47(44.68) | 10/34(29.41) | 11/13(84.62) | 0.0009 |