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Fig. 3 | Pediatric Rheumatology

Fig. 3

From: Epstein–Barr Virus encephalitis associated hemophagocytic lymphohistiocytosis in childhood-onset systemic lupus erythematosus: a case-based review

Fig. 3

The examination of bone marrow revealed evident histiocytes with hemophagocytic activity (Hematoxylin and eosin stain; original magnification, 40 \(\times\)) (a), as were increased numbers of CD8+ T cells with modest cytological atypia (b). CD20.+ B cells (c) and positive Epstein–Barr virus–encoded RNA in situ hybridization were rare (d). (Hematoxylin and eosin stain, immunohistochemistry stain; original magnification, 20 \(\times\))

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