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Fig. 4 | Pediatric Rheumatology

Fig. 4

From: The plasma metabolome of juvenile idiopathic arthritis varies according to subtype and underlying inflammatory status

Fig. 4

Biomarkers that are associated with chronic inflammation (GlycA) (A) Volcano plot for the estimated association between level of 70 primary metabolomic measures and GlycA (n = 90) from adjusted linear regressions model. A dotted line indicates padj value cut-off of 0.05. Biomarkers with padj<0.05 are labelled. (B) A scatter plot for 13 GlycA-associated biomarkers (n = 90). The distribution in the whole cohort were described by scatter plot (black dots) and the associations between GlycA and potential biomarkers were illustrated with a linear fitted line (blue). (C) Volcano plot for the estimated association between level of 70 primary metabolomic measures and hsCRP (n = 90) from adjusted linear regressions model. A dotted line indicates padj value cut-off of 0.05. Biomarkers with padj<0.05 are labelled. (D) A scatter plot for 4 hsCRP-associated biomarkers (n = 90). The distribution in the whole cohort were described by scatter plot (black dots) and the associations between hsCRP and potential biomarkers were illustrated with a linear fitted line (blue)

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