Skip to main content

Table 1 Comparison of the chemokine levels in the culture supernatants of PBMCs of patients during active period before and after stimulation with IFNɣ

From: Lack of HLH in FMF

 

CXCL9

CXCL10

IL-18

 

Before IFNγ

After IFNγ

p

Before IFNγ

After IFNγ

p

Before IFNγ

After IFNγ

p

MAS flare

46.3 (0-152.9)

58.9 (0-282.7)

0.06

2.10(0-40.3)

28.8 (0–54)

0.28

0 (0-73.5)

20.1 (0-153)

0.1

FMF flare

0 (0-13.8)

12.2(0-42.9)

0.10

0 (0–20)

0 (0-42.5)

1

73.5 (0-100)

46.8 (0-126.5)

1

HC

0 (0-12.7)

0 (0-28.3)

0.31

0 (0-10.4)

8.4 (0–18)

0.18

73.4 (0-153)

60.5 (0-231)

1

  1. MAS, Macrophage activation syndrome; FMF, Familial Mediterranean Fever, HC, healthy control; IFNγ, interferon-gamma; CXCL, chemokine (C-X-C) motif ligand
  2. p < 0.05, statistically significant