Table 5 PedsQL-GC and PedsQL-family impact scores in various subgroups of patients with cSLE
Variable | All patients (n = 91) | Depression | Anxiety | |||||
|---|---|---|---|---|---|---|---|---|
Depression (n = 29) | Non-depression (n = 62) | P-value | Anxiety (n = 45) | Non-anxiety (n = 46) | P-value |  | ||
PedsQL-GC total score | 72.2 ± 16.7 | 58.8 ± 15.3 | 78.5 ± 13.4 | < 0.001 | 61.3 ± 14.1 | 83.0 ± 11.3 | < 0.001 |  |
 Physical | 73.4 ± 20.3 | 61.9 ± 20.9 | 78.8 ± 17.8 | < 0.001 | 63.5 ± 19.7 | 83.1 ± 15.9 | < 0.001 |  |
 Psychosocial | 71.6 ± 17.1 | 57.2 ± 15.3 | 78.4 ± 13.4 | < 0.001 | 60.1 ± 14.5 | 82.9 ± 10.8 | < 0.001 |  |
 • Emotional | 69.1 ± 21.2 | 49.8 ± 16.1 | 78.1 ± 16.8 | < 0.001 | 55.2 ± 18.1 | 82.6 ± 14.0 | < 0.001 |  |
 • Social | 76.7 ± 20.7 | 61.9 ± 22.3 | 83.6 ± 15.9 | < 0.001 | 65.9 ± 20.8 | 87.2 ± 14.3 | < 0.001 |  |
 • School | 69.1 ± 21.0 | 59.8 ± 21.7 | 73.5 ± 19.4 | 0.006 | 59.1 ± 23.3 | 78.9 ± 12.3 | < 0.001 |  |
PedsQL-family impact total score | 77.9 ± 15.5 | 69.3 ± 16.3 | 81.9 ± 13.5 | 0.001 | 71.5 ± 15.8 | 84.2 ± 12.5 | < 0.001 |  |
 Parent functioning | 79.2 ± 15.9 | 70.2 ± 16.4 | 83.4 ± 13.9 | < 0.001 | 72.7 ± 16.8 | 85.5 ± 12.2 | < 0.001 |  |
 • Physical functioning | 77.2 ± 19.6 | 69.7 ± 19.9 | 80.7 ± 18.6 | 0.015 | 71.7 ± 20.2 | 82.6 ± 17.6 | 0.007 |  |
 • Emotional functioning | 76.2 ± 18.3 | 65.2 ± 17.0 | 81.4 ± 16.7 | < 0.001 | 68.6 ± 16.9 | 83.7 ± 16.7 | < 0.001 |  |
 • Social functioning | 83.4 ± 21.0 | 74.4 ± 24.6 | 87.6 ± 17.8 | 0.013 | 75.3 ± 24.9 | 91.3 ± 12.2 | < 0.001 |  |
 • Cognitive functioning | 79.8 ± 19.3 | 71.4 ± 23.3 | 83.8 ± 15.8 | 0.013 | 75.2 ± 22.2 | 84.4 ± 14.7 | 0.024 |  |
 • Communication | 80.9 ± 23.0 | 67.8 ± 28.4 | 86.6 ± 17.3 | 0.002 | 71.5 ± 25.7 | 89.5 ± 16.0 | < 0.001 |  |
 • Worry | 68.1 ± 22.4 | 61.2 ± 24.7 | 71.3 ± 20.6 | 0.062 | 60.2 ± 21.6 | 75.8 ± 20.5 | 0.001 |  |
 Family functioning | 78.6 ± 19.7 | 69.4 ± 22.3 | 83.0 ± 16.9 | 0.006 | 72.9 ± 21.3 | 84.3 ± 16.4 | 0.005 |  |
 • Daily activities | 72.4 ± 24.9 | 59.5 ± 28.2 | 78.5 ± 20.8 | 0.001 | 64.1 ± 27.6 | 80.6 ± 19.0 | 0.001 |  |
 • Family relationships | 84.8 ± 18.0 | 79.3 ± 19.9 | 87.4 ± 16.6 | 0.063 | 81.7 ± 19.0 | 87.9 ± 16.7 | 0.098 |  |