Table 2 Comparison between MPA trough levels (µg/mL) and clinical findings/MMF-related side effects in both study groups

Clinical findings

Malar rash:

Present

7

1.45 ± 2.44

0.221

10

1.03 ± 1.4

0.112

Absent

22

1.43 ± 1.8

25

1.47 ± 1.4

Oral ulcer:

Present

7

1.59 ± 2.4

0.683

3

2.52 ± 1.98

0.316

Absent

22

1.38 ± 1.81

32

1.24 ± 1.31

Alopecia

Present

7

1.59 ± 2.4

0.683

14

1.26 ± 1.37

0.533

Absent

22

1.38 ± 1.81

21

1.41 ± 1.44

Photosensitivity

Present

1

1.47

0.473

7

1.69 ± 1.48

0.248

Absent

28

1.43 ± 1.96

28

1.26 ± 1.39

Arthritis

Present

1

6.98

0.12

10

1.05 ± 1.36

0.139

Absent

28

1.24 ± 1.63

25

1.47 ± 1.42

Mayalgia

Present

0

-

-

2

2.07 ± 2.5

0.619

Absent

29

1.43 ± 1.93

33

1.3 ± 1.35

Pleurisy

Present

0

-

-

3

0.37 ± 0.21

0.133

Absent

29

1.43 ± 1.93

32

1.44 ± 1.42

Cerebritis

Present

0

-

-

1

0.6

0.8

Absent

29

1.43 ± 1.93

34

1.37 ± 1.41

Carditis

Present

0

-

-

3

0.37 ± 0.21

0.118

Absent

29

1.43 ± 1.93

32

1.44 ± 1.42

Flare

Present

13

1.25 ± 1.9

0.062

12

0.75 ± 0.92

*0.027

Absent

16

1.59 ± 1.997

23

1.66 ± 1.51

Side effects

Gastritis

Present

8

1.65 ± 2.25

0.769

10

2.42 ± 1.76

*0.007

Absent

21

1.35 ± 1.84

25

0.92 ± 0.96

Leucopenia

Present

1

1.82

0.231

6

1.41 ± 1.69

0.526

Absent

28

1.42 ± 1.96

29

1.34 ± 1.36

Infection

Present

1

0.5

0.338

4

1.84 ± 1.39

0.213

Absent

28

1.47 ± 1.95

31

1.28 ± 1.4