Table 1 Characteristics of the children at uveitis diagnosis according to the presence (MSGB+) or absence (MSGB–) of granuloma on minor salivary gland biopsy (MSGB)

Girls/boys

12/14

6/6

6/8

1

Age at uveitis onset, years, median (min–max)

11.6 (4.2–16.5)

12.2 (6.1–13.7)

10.6 (4.2–16.5)

0.09

Age > 10 years at uveitis onset, n (%)

15 (58%)

10 (83%)

5 (36%)

0.02

Delay between uveitis diagnosis and onset, days, median (min–max)

28 (2–394)

22 (2–394)

30 (2–245)

0.81

Familial history of autoimmune and/or inflammatory disease, n (%)

6 (23%)

4 (33%)

2 (14%)

0.37

Uveitis characteristics, n (%)

Redness and/or pain

23 (88%)

12 (100%)

11 (79%)

0.22

Bilateral uveitis

24 (92%)

12 (100%)

12 (86%)

0.48

Pan-uveitis

25 (96%)

12 (100%)

13 (93%)

1

Synechiae

16 (62%)

6 (50%)

10 (71%)

0.42

Papillary oedema

21 (81%)

10 (83%)

11 (79%)

1

Macular oedema

6 (23%)

0 (0)

6 (43%)

0.02

Visual acuity of the weaker eye, median (min–max)

8.5(1–10)/10

9(1–10)/10

6.5(2–10)/10

0.22

Visual acuity of the weaker eye ≤ 4

8 (31%)

2 (17%)

6 (43%)

0.22

Extraocular involvement, n (%)

General signs

9 (35%)

8 (67%)

1 (7%)

0.003

Organ involvement

13 (50%)

10 (83%)

3 (21%)

0.005

Laboratory results, n, positive/performed

Lymphopenia < 1.5 10⁹/L

3/25 (12%)

1/12 (8%)

2/13 (15%)

1

Elevated CRP and/or ESR

10/25 (40%)

7/12 (58%)

3/13 (23%)

0.11

Polyclonal hypergammaglobulinaemia

9/24 (36%)

7/11 (64%)

2/13 (15%)

0.03

Elevated ACE

0/22

0/11

0/12

1

Time to MSGB after uveitis diagnosis, days, median (min–max)

17 (2–86)

7 (2–69)

21 (4–86)

0.24

MSGB performed after systemic corticosteroid initiation, n (%)

8 (31%)

5 (42%)

3 (21%)

0.4