Skip to main content

Table 2 Comparison between patients with childhood-onset SLE with early- and late-onset serositis

From: Serositis as an indicator of poor prognosis in pediatric systemic lupus erythematosus

 

cSLE with early-onset serositis

(N = 19, 50%)

cSLE with late-onset serositis

(N = 19, 50%)

P-value

Female: Male, n (%)

16:3 (84.21%)

17:2 (89.47%)

1.000

Age at diagnosis of SLE, mean ± SD, years

12.87 ± 3.59

12.17 ± 2.54

0.507

Follow-up duration, mean ± SD, years

4.33 ± 4.99

9.70 ± 5.73

0.004

Modified SLEDAI-2 K, mean ± SD

15.52 ± 5.18

13.57 ± 4.58

0.240

Lupus nephritis, n (%)

13 (68.42%)

18 (94.73%)

0.094

End-stage renal disease, n (%)

4 (21.05%)

14 (73.68%)

0.003

Mortality, n (%)

4 (21.05%)

11 (57.89%)

0.046

Age at death, mean ± SD, years

14.25 ± 2.46

18.04 ± 4.80

0.183

  1. cSLE, childhood-onset systemic lupus erythematosus; SLE, systemic lupus erythematosus; SD, standard deviation; SLEDAI-2 K, Systemic Lupus Erythematosus Disease Activity Index 2000