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Table 3 Comparison of childhood-onset systemic lupus erythematosus (SLE) according to serositis severity

From: Serositis as an indicator of poor prognosis in pediatric systemic lupus erythematosus

 

cSLE with large and moderate serositis (N = 15, 39.47%)

cSLE with small serositis (N = 23, 60.52%)

P-value

Female: Male, n (%)

14:1 (93.3%)

19:4 (82.60%)

0.641

Age at diagnosis of SLE, mean ± SD, years

13.40 ± 2.18

11.94 ± 3.50

0.168

Follow-up duration, mean ± SD, years

5.82 ± 6.46

7.80 ± 5.56

0.344

Performance of effusion drainage, n (%)

10 (66.66%)

6 (26.08%)

0.032

Modified SLEDAI-2 K, mean ± SD

14.20 ± 4.95

14.78 ± 4.99

0.733

Lupus nephritis, n (%)

12 (80%)

19 (82.60%)

0.821

End-stage renal disease, n (%)

9 (60%)

9 (39.13%)

0.353

Mortality, n (%)

7 (46.66%)

8 (34.78%)

0.694

Age at death, mean ± SD, years

15.13 ± 2.49

18.69 ± 5.35

0.156

  1. cSLE, childhood-onset systemic lupus erythematosus; SLE, systemic lupus erythematosus; SD, standard deviation; SLEDAI-2 K, Systemic Lupus Erythematosus Disease Activity Index 2000