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Table 4 Risk of death in patients with childhood-onset SLE by multivariate Cox regression analysis

From: Serositis as an indicator of poor prognosis in pediatric systemic lupus erythematosus

 

cSLE deceased (N = 20, 10.81%)

cSLE survivors (N = 165, 89.18%)

Hazard ratio

95% Confidence interval

P-value

Female, n (%)

18 (90%)

137 (83.03%)

1.830

0.330–10.166

0.48

Age at diagnosis of SLE (years)

12.66 ± 2.80

13.55 ± 3.20

1.023

0.868–1.205

0.787

Serositis, n (%)

15 (75%)

23 (13.93%)

5.585

1.853–17.80

0.003

End-stage renal disease, n (%)

16 (84.21%)

12 (7.27%)

13.956

3.822–50.964

< 0.001

Modified SLEDAI-2 K > 8, n (%)

15 (75%)

108 (65.45%)

0.539

0.156–1.863

0.328

  1. Age is expressed as mean ± SD
  2. cSLE, childhood-onset systemic lupus erythematosus; SLE, systemic lupus erythematosus; SLEDAI-2 K, Systemic Lupus Erythematosus Disease Activity Index 2000