Table 2 Clinical and laboratory characteristics at admission of febrile JSLE patients, stratified by confirmed bacterial infection
From: Bacterial infection in patients with juvenile systemic lupus erythematosus and fever
Characteristic (n) | Median (IQR) (n) | p-value | ||
|---|---|---|---|---|
n = 116 | Confirmed Infection (cases) (n = 20) | No infection confirmation (controls) (n = 96) | ||
Age in years | 116 | 14,5 (12 – 16) | 15 (13–16) | 0,64 |
Fever duration in days | 115 | 2 (1 – 7) | 4 (1 – 15) | 0,48 |
Temperature (°C) | 116 | 38 (38 – 39) | 38 (38 – 39) | 0,82 |
PCT (ng/mL) | 26 | 0,57 (0,16 – 4,51) | 0,14 (0,06 – 0,30) | 0,20 |
CRP (mg/L) | 111 | 42,5 (2,70 – 115) | 14,6 (3,06 – 45,6) | 0,77 |
ESR (mm/hra) | 97 | 90 (49 – 103) | 80 (35 – 108) | 0,56 |
Ferritin (ng/mL) | 66 | 428 (199 – 640) | 220 (118 – 639) | 0,07 |
Leukocytes (/ml3) | 115 | 5515 (3860 – 10192) | 6700 (4800 – 9390) | 0,48 |
Lymphocytes (/ml3) | 115 | 1030 (722–1412) | 1400 (920–2050) | 0,03 |
Neutrophils (/ml3) | 115 | 3940 (2135 – 8625) | 4530 (3070 – 6700) | 0,83 |
Hemoglobin (gr/dl) | 115 | 10,0 (8,3 – 11,8) | 10,1 (8,6 – 11,8) | 0,6 |
Platelets (× 103/ml3) | 115 | 217,5 (160,25 – 30825) | 277 (210 – 396) | 0,23 |
NLR | 115 | 5,75 (1,46 – 9,81) | 3,19 (1,85 – 5,97) | 0,43 |
VES/PCR | 94 | 2,4 (0,71 – 28,6) | 4,9 (1,6 – 17,6) | 0,28 |
IPL | 115 | 242 (154 – 334) | 200 (134 – 310) | 0,20 |
ILC4 | 96 | 110 (42,5 – 153) | 171 (70 – 440) | 0.01 |
C3 (mg/dl) | 97 | 58,3 (40 – 89,9) | 52,5 (32,2 – 111) | 0,96 |
C4 (mg/dl) | 97 | 11,9 (6 – 20) | 6,9 (3,2 – 20) | 0,28 |
SLEDAI-2 k | 116 | 23 (3—41) | 19 (11—28) | 0,74 |