FDG-PET/CT as a useful tool for disease activity assessment in large vessel vasculitis in childhood

Table 1 Patient characteristics

Parameter	Patients
Parameter	Patient 1	Patient 2	Patient 3	Patient 4
Gender	female	female	female	female
Age at diagnosis of TA	17 y	13 y	13 y	13 y
Symptoms at initial manifestation	Fever	Fever	Fever	Fever
	Fatigue	Fatigue	Fatigue	Fatigue
	Headache, Art. Hypertension	Malaise, Erythema nodosum	Night sweats, Weight loss	Palpatory reduced pulse left upper extremity, Blood pressure difference lower to upper extremity
Laboratory finding
CrP (N: < 5 mg/l)	27	63	89	149
ESR (mm/h)	83	88	76	> 100
SAA (N: < 40 mg/l)	105	> 120	> 120	> 120
ANA	negative	negative	negative	positive
Initial therapy	Prednisolon	Prednisolon	Prednisolon	Prednisolon
Maintenance therapy	Tocilizumab	Tocilizumab	Tocilizumab	Tocilizumab
Duration of tocilizumab	22 months	12 months	61 months	More than 96 months, still ongoing
Previous illnesses	Crohn`s disease	Uveitis intermedia		Kawasaki Syndrome
	Akne inversa	Juvenile idiopathic arthritis
	Psoriasis inversa	Celiac disease
Previous medication	Adalimumab	Adalimumab
	Anakinra	Methotrexat
	Infliximab	Prednisolon
	Methotrexat
	Ustekinumab
	Vedolizumab
Last medication before TA onset	Vedolizumab	Adalimumab

ISSN: 1546-0096