Table 6 PostHoc test between time points
| Â | Estimated marginal means | p values | ||||
|---|---|---|---|---|---|---|
| Â | Time 1 | Time 2 | Time 3 | Time 1 vs. 2 | Time 1 vs. 3 | Time 2 vs. 3 |
Subpopulation | Mean ± SD and 95% CI | |||||
CD3+ (abs.) | 1798.0 ± 463.59 1652.0-1943.0 | 1733.0 ± 663.24 1581.0-1886.0 | 1723.0 ± 583.77 1573.0-1874.0 | 0.960 | 0.727 | 1.000 |
CD3/CD25+ (%) | 9.87 ± 2.86 8.98–10.8 | 9.64 ± 3.95 8.73–10.6 | 11.4 ± 3.52 10.48–12.3 | 1.000 | < 0.001 | < 0.001 |
CD3/CD45RA (%) | 41.9 ± 9.35 39.0-44.9 | 44.6 ± 13.08 41.5–47.6 | 41.3 ± 11.60 38,2-44.3 | 0.090 | 1.000 | 0.021 |
CD3/CD45RO (%) | 32.2 ± 7.75 29.8–34.7 | 30.6 ± 10.58 28.1–33.0 | 31.3 ± 9.45 28.8–33.7 | 0.067 | 0.571 | 0.953 |
CD4+ (abs.) | 994.0 ± 252.35 915.0-1073.0 | 987.0 ± 360.44 904.0-1071.0 | 970.0 ± 317.99 888.0-1052.0 | 1.000 | 1.000 | 1.000 |
CD8+ (abs.) | 667.0 ± 236.54 593.0-742.0 | 628.0 ± 335.49 551.0-706.0 | 639.0 ± 296.49 562.0-715.0 | 0.564 | 0.967 | 1.000 |
CD19+ (abs.) | 252.0 ± 126.49 213.0-292.0 | 242.0 ± 185.81 199.0-284.0 | 264.0 ± 162.07 222.0-306.0 | 1.000 | 1.000 | 1.000 |
Lymphocyte (abs.) | 2420 ± 600 2240–2600 | 2330 ± 820 2150–2520 | 2310 ± 720 2130–2500 | 0.848 | 0.579 | 1.000 |
Naive B (%) | 78.9 ± 8.66 76.3–81.6 | 80.0 ± 11.61 77.3–82.7 | 76.3 ± 10.37 73.6–79.0 | 1.000 | 0.107 | 0.010 |
NK cell (%) | 12.6 ± 4.69 11.2–14.0 | 12.0 ± 6.37 10.5–13.4 | 12.1 ± 5.69 10.6–13.5 | 1.000 | 1.000 | 1.000 |
NKT cell (%) | 5.30 ± 5.18 3.73–6.87 | 5.05 ± 6.93 3.43–6.66 | 6.74 ± 6.27 5.14–8.35 | 1.000 | 0.237 | 0.125 |
Switched B (%) | 11.8 ± 6.23 9.91–13.7 | 13.1 ± 8.41 11.16-15.0 | 14.0 ± 7.48 12.08–15.9 | 0.611 | 0.093 | 1.000 |