Fig. 2

Frequency Distribution of Cardiopulmonary Assessment Tools and Treatment Use by Pediatric Rheumatologists in Juvenile Systemic Sclerosis. Cells A-D display the frequency of assessment tools and treatments used in juvenile systemic sclerosis by region, Gross Domestic Product (GDP) per capita expressed in international dollars, and patient volume. Each bar plot compares assessment tool/treatment use across groups. Full PFT includes spirometry, lung volumes, and diffusion capacity. Statistical significance (p < 0.05) is indicated by an asterisk (*). Abbreviations: CYC = cyclophosphamide, Echo = echocardiogram, HRCT = high-resolution computed tomography, MMF = mycophenolate mofetil, MRA = magnetic resonance angiography, MTX = methotrexate, PO = by mouth, PFT = pulmonary function test, RTX = rituximab, 6MWT = six-minute walk test