Table 1 Baseline characteristics of patients with juvenile systemic sclerosis

Male: Female (n)

22:42

16:36

Age of onset (years-old)

11.4(6.4,13.9)

11.8(6.0,14.0)

Time from onset to diagnosis (years)

0.9(0.5,2.3)

0.8(0.5,2.3)

Number of organs involved in the course of the disease

 mRSS

12.0(8.0,17.0)

12.0(8.0,16.0)

 Raynaud's phenomenon

48/64(75.0%)

38/52(73.1%)

 Respiratory system

44/64(68.8%)

36/52(69.2%)

 Joint system

36/64(56.3%)

30/52(57.7%)

 Digestive system

23/64(35.9%)

20/52(38.5%)

 Haematological system

18/63(28.6%)

15/52(28.8%)

 Musculoskeletal System

13/64(20.3%)

10/52(19.2%)

 Cardiovascular System

11/63(17.5%)

11/51(21.6%)

 Nervous System

5/64(7.8%)

4/52(7.7%)

 Urinary System

1/64(1.6%)

1/52(1.9%)

Laboratory tests at baseline

 Elevated CRP

16/53(30.2%)

13/43(30.2%)

 Elevated ESR

16/59(27.1%)

13/48(27.1%)

 Anaemia

6/62(9.7%)

5/51(9.8%)

 Abnormal liver function

16/62(25.8%)

14/51(27.5%)

 Hypoalbuminaemia

12/53(22.6%)

9/45(20.0%)

 Hypocomplementemia

14/57(24.6%)

12/46(26.1%)

 Positive anti-Scl-70 antibodies

36/64(56.3%)

29/52(55.8%)

 Presence of ≥ 2 autoantibodies

46/64(71.9%)

38/52(73.1%)